Yes, there are multiple flights from Chiang Mai to Buffalo for under ฿ 41,951. The cheapest flight booked recently is on Multiple Airlines for just ฿ 39,883, but on average you can expect to pay ฿ 39,913.
There are no direct flights from Chiang Mai to Buffalo, but Cheapflights can provide you with all the information you need to find the fastest route with the fewest stops.
When travelling, it's generally smart to pack in preparation for rain or any other conditions that may arise. The rainfall in Chiang Mai is roughly less than Buffalo. You can assume this to be the case over the next 1 days.
We forecast the temperature to be around the 37 °Cs in April, on average. The temperature in Buffalo is generally colder than in Chiang Mai. Book flights in a timely manner in correlation to your departure date.